Nicotine Dependence clinical trials at UC Cancer

• Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power

  open to eligible people ages 21 years and up

  This study will examine the short-term cardiovascular (CV) effects of e-cigarette device power in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21). The specific aim is to determine the impact of e-cigarette power on nicotine pharmacology, systemic exposure to toxic volatile organic compounds (VOCs), and short-term cardiovascular effects.

  at UCSF

• Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH

  open to eligible people ages 21-70

  This study will examine the short-term cardiovascular (CV) effects of e-liquid pH in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21). The specific aim of the study is to assess the impact of changes in e-liquid pH on nicotine pharmacokinetics, cardiovascular, and subjective effects of e-cigarettes.

  at UCSF

• THC Crossover Study

  open to eligible people ages 21 years and up

  This is a randomized, crossover study enrolling experienced dual cannabis-tobacco smokers (N=18) to describe the differences in THC and toxicant exposure, examining pharmacokinetic, subjective, and cardiovascular effects from smoking and vaping dry herb cannabis. This study will also examine the differences in toxicant exposure and cardiovascular disease risk between smoking cannabis and smoking tobacco cigarettes.

  at UCSF

Last updated: November 30, 2021