Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCLA
Dates
study started
estimated completion
Principal Investigator
Tara M McCannel (ucla)Lynn Gordon, MD, PhD (ucla)Ben Glasgow, MD (ucla)Nagesh P Rao (ucla)

Description

Summary

Patients who are diagnosed with choroidal melanoma and undergo I-125 plaque or enucleation surgery consent to participate in the study. A tumor sample taken during surgery is studied in the lab for genetic features. These features and features of subjects' clinical course are recorded. Analysis of the data may identify genetic features that are indicative of prognostic factors including risk of metastasis.

Official Title

Molecular and Cytogenetic Studies of Ocular Melanoma

Details

The Jules Stein Eye Institute Ocular Melanoma Research Group is conducting cytogenetic studies of choroidal melanoma to improve the screening of biopsy samples of choroidal melanoma through cytogenetic analysis. Our goal is to identify molecular probes that specifically target regions of chromosomes that undergo changes characteristic of metastatic choroidal melanoma.

Keywords

Choroidal Melanoma Choroidal Malignant Melanoma Ocular Melanoma Uveal Melanoma Melanoma

Eligibility

You can join if…

Open to people ages 18 years and up

  1. Patient with diagnosis of ocular melanoma
  2. Patient with local treatment plan for ocular melanoma- plaque brachytherapy or enucleation
  3. Patient 18 years of age or older
  4. Archival enucleation specimens with diagnosis of ocular melanoma

You CAN'T join if...

  1. Patient who refuses local melanoma treatment
  2. Patient who refuses to participate in this study

Location

  • Jules Stein Eye Institute accepting new patients
    Los Angeles California 90095 United States

Lead Scientists at UC Cancer

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Jonsson Comprehensive Cancer Center
ID
NCT00344799
Study Type
Observational
Last Updated