Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCLA
Dates
study started
estimated completion
Principal Investigator
Michael L. Steinberg (ucla)

Description

Summary

This research trial studies the effect of radiation therapy on tumor immunity. Standard radiation therapy destroys tumor cells. In response to tumor cell death caused by radiation therapy, the body has an ability to stimulate an anti-tumor response (immunity), but this response is often ineffective in shrinking tumor tissue. Collecting samples of blood from patients before, during, and after radiation therapy to study in the laboratory may help doctors learn more about the effects of radiation therapy on anti-tumor response.

Official Title

The Effect of Radiation Therapy on Tumor Immunity

Details

PRIMARY OBJECTIVES:

  1. To assess the effect of radiation therapy on tumor immunity.

OUTLINE:

Samples of blood are collected before, during, and within two weeks after radiation therapy and then stored for analysis of anti-tumor immunity.

Keywords

Malignant Neoplasm Neoplasms cytology specimen collection procedure laboratory biomarker analysis Ancillary-Correlative (blood banking)

Eligibility

You can join if…

Open to people ages 18 years and up

  • Signed and dated Institutional Review Board (IRB)-approved Informed Consent form for the study
  • Received an explanation of the study, including satisfactory answers to all questions related to the proposed research
  • Is undergoing physician directed radiation treatment

You CAN'T join if...

  • The potential Subject is unwilling or hesitant to participate for any reason and/or fails to complete the appropriate Informed Consent form

Location

  • Jonsson Comprehensive Cancer Center accepting new patients
    Los Angeles California 90095 United States

Lead Scientist at UC Cancer

  • Michael L. Steinberg (ucla)
    Professor of Clinical , Radiation Oncology. Authored (or co-authored) 96 research publications.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Jonsson Comprehensive Cancer Center
ID
NCT02310594
Study Type
Observational
Last Updated